Zissis Oikonomou was born in Skiathos in 1911. He learned German and Italian, and during the Greek-Italian war of '40 he served as an interpreter. He lived in Athens and worked with literary magazines. His first appearance in literature came in 1930 with lyrics publications in the journal "Nea Genia" and in 1934 published his first poetry collection, entitled "The Epic Tale of Vegetative Metals". Since the mid of '50s and until 1976 he resign from publications and worked on research in the field of glossology, sociology and politics.
Zissis Oikonomou belongs to the inter-war generation of Greek poets. His poetic course covered a broad thematic and stylistic range, with the goal of the poet seeking a single worldview that draws on all aspects of absolute knowledge. With starting point the optimistic worldview futurism and surrealism and the glorification of engineering technology passed quickly in the process of folding and the reservation in front of western rationalism and turned towards an individualistic worldview, which is influenced by his interest in Eastern religions, Buddhism and especially by philosophers such as Schopenhauer, and Berntiagief Kaizerligk. The searches also had an impact on poetry, which led gradually to a reason more and more simple and drastic.
In 1977 he received the National Prize for Poetry from Athen's Academy , for all his poetic work and especially for his book "cloudless silence," and in 1995 won the National Prize for Poetry for his book "Chronicle of the New Orderliness for New Era" . He also practised in theater.
In old age he returned to his hometown where he began working with maritime and agricultural works. He died in 2005 and left part of his property in the Municipality of Skiathos to be used for cultural purposes.